װ ȭа ΰ

Content on this page requires a newer version of Adobe Flash Player.

Get Adobe Flash player

 
ۼ : 16-01-28 11:40
[16.01]ȯ -Synthesis of Branched Alkylboronates by Copper-Catalyzed Allylic Substitution Reactions of Allylic Chlorides with 1,1-Diborylalkanes
 ۾ :
ȸ : 1,407  

Synthesis of Branched Alkylboronates by Copper-Catalyzed Allylic Substitution Reactions of Allylic Chlorides with 1,1-Diborylalkanes

 


-Junghoon Kim, Sangwoo Park, Jinyoung Park,  Seung Hwan Cho*

 


Reported herein is a copper-catalyzed SN2-selective allylic substitution reaction using readily accessible allylic chlorides and 1,1-diborylalkanes, a reaction which proceeds with chemoselective CB bond activation of the 1,1-diborylalkanes. In the presence of a catalytic amount of [Cu(IMes)Cl] [IMes=1,3-bis(2,4,6-trimethylphenyl)imidazole-2-ylidene] and LiOtBu as a base, a range of primary and secondary allylic chlorides undergo the SN2-selective allylic substitution reaction to produce branched alkylboronates. The synthetic utilities of the obtained alkylboronates are also presented.

 

˸ȭ ġȯ ź-ź ȭչ ϴµ ߿ ̴Ư ˸ ˸ȭ ġȯ ڸ ü ϴ ȭ о߿ ߿

̿ ˸ſ N-heterocyclic carbene   1,1-ų ̺ؼ ȭչ ؼ ۿ⸦ ȭ Ȱȭ Ͽ ˸ڸ ȭչ ڸ ˸ȭ ġȯ Ͽ

˸ȭ ġȯ Ī ռ о߷ Ȯ   κ ü ü ȭչ ռϴµ ο ɼ Ͽ

̷ ȭ ȰԹɹ (Angewandte Chemie) ȮǾ.


 
 

Total 72
ȣ     ۾ ¥ ȸ
72 [2017.07]ȯ Diastereo- and Enantioselective Synthesis of -Aminoboronate Esters by Copper(I)-Catalyzed 1,2-Addition of 1,1-Bis[(pinacolato)boryl]alkanes to Imines 07-20 30
71 [2017.06]ڹ Tattooing Dye as a Green Electrode Material for Lithium Batteries 07-03 100
70 [2017.04]輺 Cancer-Microenvironment-Sensitive Activatable Quantum Dot Probe in the Second Near-Infrared Window 04-20 394
69 [2017.01]ȯ Chemoselective Coupling of 1,1-Bis[(pinacolato)boryl]alkanes for the Transition-Metal-Free Borylation of Aryl and Vinyl Halides: A Combined Experimental and Theoretical Invesitigation 01-02 886
68 [2016.11]ڹ 1 Volt-Driven Superfast Polymer Actuators Based on Single Ion Conductors 11-16 857
67 [2016.09]α Ultrathin and Flat Layer Black Phosphorus Fabricated by Reactive Oxygen and Water Rinse 09-22 925
66 [2016.08]ö Unique Crystallization of Fullerenes: Fullerene Flowers 08-30 529
65 [2016.08]ö Nanocomb Architecture Design Using Germanium Selenide as High Performance Lithium Storage Material 08-29 781
64 [2016.08]ؿ Visualization and Quantification of MicroRNA in a Single Cell Using Atomic Force Microscopy 08-17 733
63 [2016.06]ȯ Transition-Metal-Free Regioselective Alkylation of Pyridine N-Oxides Using 1,1-Diborylalkanes as Alkylating Reagents 06-29 959
62 [2016.05]ؿ Quantification of Fewer Than Ten Copies of a DNA Biomarker without Amplification or Labeling 05-16 934
61 [1603] -Light-Induced Acid Generation on a Gatekeeper for Smart Nitric Oxide Delivery 03-30 1113
60 [16.01]ȯ -Synthesis of Branched Alkylboronates by Copper-Catalyzed Allylic Substitution Reactions of Allylic Chlorides with 1,1-Diborylalkanes 01-28 1408
59 [16.01] - Synergistic Nanomedicine by Combined Gene and Photothermal therapy 01-27 1054
58 [15.11] - A chemical inhibitor of the Skp2/p300 interaction that promotes p53-mediated apoptosis 11-26 1352
 1  2  3  4  5  

Content on this page requires a newer version of Adobe Flash Player.

Get Adobe Flash player