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ۼ : 12-09-06 09:34
[12.07] -Bioreducible polymers for gene silencing and delivery
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 ۾ :
ȸ : 1,736  

Bioreducible polymers for gene silencing and delivery
-Sejin Son, Ran Namgung, Jihoon Kim, Kaushik Singha, Won Jong Kim *

This Account discusses current research trends and recent progress in the disulfide chemistry enabling novel and versatile designs of reducible polymeric gene delivery systems. We present strategies for the introduction of disulfide bonds into polymers. These representative examples and their respective outcomes elaborate the benefit and efficiency of disulfides at the individual stages of gene delivery


 
 

Total 77
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31 [13.07]ڹ -Fast Low Voltage Electroactive Actuators Using Nanostructured Polymer Electrolytes 07-30 1695
30 [13.07] -Photothermally Triggered Cytosolic Drug Delivery via Endosome Disruption Using a Functionalized Reduced Graphene Oxide 07-17 1478
29 [13.07]ڹ -Blue-Emitting Self-Assembled Polymer Electrolytes for Fast, Sensitive, Label-Free Detection of Cu(II) Ions in Aqueous Media 07-08 1224
28 [13.06]ö -Catalyst-free Direct Growth of a Single to a Few Layers of Graphene on a Germanium Nanowire for the Anode Material of a Lithium Battery 06-19 1362
27 [13.4]⹮ -Free-Standing, Single-Monomer-Thick Two-Dimensional Polymers through Covalent Self-Assembly in Solution 11-25 1256
26 [13.3]⹮ -Supramolecular Velcro for Reversible Underwater Adhesion 11-25 1133
25 [13.01] -Active Role of Proton in Excited State Intramolecular Proton Transfer Reaction 06-19 1427
24 [13.01]μ -Reversible and Cyclical Transformations between Solid and Hollow Nanostructures in Confined Reactions of Manganese Oxide and Silica within Nanosized Spheres 02-06 1650
23 [12.07] -Bioreducible polymers for gene silencing and delivery 09-06 1737
22 [12.07]ؿ - Following the DNA Ligation of a Single Duplex Using Atomic Force Microscopy 08-01 1650
21 [12.06]μ - Electroless Pt Deposition on Mn3O4 Nanoparticles via the Galvanic Replacement Process 07-03 1949
20 [12.06]Ž± -Surface-Dependent, Ligand-Mediated Photochemical Etching of CdSe Nanoplatelets 06-14 1640
19 [12.05]⹮ -In Situ Supramolecular Assembly and ModularModification of Hyaluronic Acid Hydrogels for 3D Cellular Engineering 11-25 950
18 [12.01] -Coherent Electronic and Phononic Oscillations in Single-Walled 03-05 1865
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